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JAK2 antibody (pTyr1007, pTyr1008)

JAK2 Reactivity: Human, Rat, Mouse WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7265246
  • Target See all JAK2 Antibodies
    JAK2 (Janus Kinase 2 (JAK2))
    Binding Specificity
    • 36
    • 33
    • 16
    • 16
    • 12
    • 10
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr1007, pTyr1008
    Reactivity
    • 172
    • 100
    • 96
    • 18
    • 18
    • 3
    • 2
    • 2
    • 1
    Human, Rat, Mouse
    Host
    • 174
    • 6
    • 2
    Rabbit
    Clonality
    • 158
    • 24
    Polyclonal
    Conjugate
    • 92
    • 15
    • 9
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This JAK2 antibody is un-conjugated
    Application
    • 130
    • 81
    • 61
    • 57
    • 29
    • 27
    • 25
    • 22
    • 17
    • 13
    • 10
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    Phosphorylated antibody
    Purification
    Affinity purification
    Immunogen
    A synthetic phosphorylated peptide around Y1007 & Y1008 of human Jak2 (NP_004963.1).
    Isotype
    IgG
    Top Product
    Discover our top product JAK2 Primary Antibody
  • Application Notes
    WB 1:500-1:1000 IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    JAK2 (Janus Kinase 2 (JAK2))
    Alternative Name
    Jak2 (JAK2 Products)
    Synonyms
    JAK2bCA antibody, jak2 antibody, JTK10 antibody, THCYT3 antibody, AI504024 antibody, C81284 antibody, Fd17 antibody, JAK-2 antibody, Janus kinase 2b antibody, Janus kinase 2 antibody, jak2b antibody, JAK2 antibody, Jak2 antibody
    Background
    This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.
    Molecular Weight

    Observed_MW: 131 kDa

    Calculated_MW: 130 kDa

    Gene ID
    3717
    UniProt
    O60674
    Pathways
    JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response
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