CLEC9A antibody
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- Target See all CLEC9A Antibodies
- CLEC9A (C-Type Lectin Domain Family 9, Member A (CLEC9A))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CLEC9A antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Specificity
- The mouse monoclonal antibody 8F9 recognizes an extracellular epitope of CD370 / CLEC9A (DNGR1), a type II transmembrane protein functioning as an endocytic receptor on BDCA31+ dendritic cells and on a subset of CD14+ CD16- monocytes.
- Purification
- Purified by protein-A affinity chromatography.
- Immunogen
- RBL-2H3 cells expressing human CLEC9A fused to an HA epitope
- Clone
- 8F9
- Isotype
- IgG2a
- Top Product
- Discover our top product CLEC9A Primary Antibody
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anti-C-Type Lectin Domain Family 9, Member A (CLEC9A) (AA 57-241) antibody
CLEC9A Reactivity: Human WB, ELISA, FACS, IHC, ICC, Neut Host: Mouse Monoclonal 5C7A7 unconjugated
anti-C-Type Lectin Domain Family 9, Member A (CLEC9A) antibody (PE)CLEC9A Reactivity: Human FACS Host: Mouse Monoclonal 8F9 PE
anti-C-Type Lectin Domain Family 9, Member A (CLEC9A) (AA 1-241) antibodyCLEC9A Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-C-Type Lectin Domain Family 9, Member A (CLEC9A) (AA 101-200) antibodyCLEC9A Reactivity: Human, Mouse, Rat WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-C-Type Lectin Domain Family 9, Member A (CLEC9A) (AA 146-173) antibodyCLEC9A Reactivity: Human WB Host: Rabbit Polyclonal RB37676 unconjugated
anti-C-Type Lectin Domain Family 9, Member A (CLEC9A) antibodyCLEC9A Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-C-Type Lectin Domain Family 9, Member A (CLEC9A) antibodyCLEC9A Reactivity: Human ELISA, FACS, IF, Coat Host: Mouse Monoclonal 8F9 unconjugated
anti-C-Type Lectin Domain Family 9, Member A (CLEC9A) (AA 1-241) antibodyCLEC9A Reactivity: Human WB Host: Mouse Polyclonal unconjugated
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- Application Notes
- Flow cytometry: Recommended dilution: 1-4 μg/mL
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C. Do not freeze.
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- Target
- CLEC9A (C-Type Lectin Domain Family 9, Member A (CLEC9A))
- Alternative Name
- CD370 (CLEC9A Products)
- Synonyms
- 9830005G06Rik antibody, DNGR-1 antibody, DNGR1 antibody, UNQ9341 antibody, RGD1562513 antibody, C-type lectin domain family 9, member a antibody, C-type lectin domain containing 9A antibody, C-type lectin domain family 9, member A antibody, Clec9a antibody, CLEC9A antibody
- Background
- C-type lectin domain containing 9A,CD370 / CLEC9A, also known as DNGR1, is a type II transmembrane glycoprotein with extracellular C-type lectin domain and intracellular ITAM-containing domain. Its expression is restricted to BDCA3+ conventional dendritic cells and to a subset of CD14+ CD16- monocytes. CD370 serves as a receptor for ubiquitous preformed acid-labile protein associated ligands that are exposed when the cell membrane is damaged, such as on necrotic cells. Its triggering by these ligands mediates recruitment and activation of the tyrosine kinase Syk and leads to their cross-presentation to the immune system.,CLEC9A, DNGR1, DNGR-1, UNQ9341
- Gene ID
- 283420
- UniProt
- Q6UXN8
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