ADCY3 antibody (3rd Extracellular Loop) (Atto 488)

Catalog No. ABIN7042893

Product Details anti-ADCY3 Antibody (Atto 488)

Target: ADCY3 (Adenylate Cyclase 3 (ADCY3))

Binding Specificity: 3rd Extracellular Loop, AA 285-299

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY3 antibody is conjugated to Atto 488

Application: Immunofluorescence (IF), Immunocytochemistry (ICC), Live Cell Imaging (LCI)

Characteristics: Anti-Adenylate Cyclase 3 (AC3) (extracellular) Antibody (ABIN7042892, ABIN7043932 and ABIN7043933)) is a highly specific antibody directed against an extracellular epitope of the rat protein. The antibody can be used in western blot, immunohistochemistry and live cell imaging applications. The antibody recognizes an extracellular epitope and thus is ideal for detecting ADCY3 in living cells. It has been designed to recognize ADCY3 from human, rat and mouse samples. \nAnti-Adenylate Cyclase 3 (AC3) (extracellular)-ATTO Fluor-488 Antibody (#ABIN7042893) is directly labeled with an ATTO-488 fluorescent dye. ATTO dyes are characterized by strong absorption (high extinction coefficient), high fluorescence quantum yield, and high photo-stability. The ATTO-488 label is analogous to the well known dye fluorescein isothiocyanate (FITC) and can be used with filters typically used to detect FITC. Anti-Adenylate Cyclase 3 (AC3) (extracellular)-ATTO Fluor-488 Antibody has been tested in live cell imaging applications and is especially suited for experiments requiring simultaneous labeling of different markers.

Purification: Affinity purified on immobilized antigen.

Immunogen:

Immunogen: Synthetic peptide

Immunogen Sequence: (C)KHVADEMLKDMKKDE, corresponding to amino acid residues 285-299 of rat ADCY3

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: 50 μL double distilled water (DDW).

Concentration: 1 mg/mL

Buffer: Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1 % BSA, 0.05 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: RT,4 °C,-20 °C

Storage Comment:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Target Details for ADCY3

Target: ADCY3 (Adenylate Cyclase 3 (ADCY3))

Alternative Name: Adenylate Cyclase 3 (AC3) (ADCY3 Products)

Synonyms: ADCY8 antibody, adcy3 antibody, si:ch211-153j24.5 antibody, Adcy3 antibody, ADCY3 antibody, Amac3 antibody, GB11637 antibody, AC3 antibody, mKIAA0511 antibody, adenylate cyclase 3 antibody, adenylate cyclase 3b antibody, DnaJ heat shock protein family (Hsp40) member C27 antibody, ADCY3 antibody, adcy3b antibody, dnajc27 antibody, Ac3 antibody, Adcy3 antibody

Background: Alternative names: Adenylate Cyclase 3 (AC3), Adenylate cyclase type 3, Adenylate cyclase type III, AC-III, ATP pyrophosphate-lyase 3, Adenylate cyclase olfactive type, Adenylyl cyclase 3, ADCY3

Gene ID: 64508

NCBI Accession: NM_001320613

UniProt: P21932

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma