CACNA1C antibody (Intracellular) (Atto 488)

Catalog No. ABIN7042998

Product Details anti-CACNA1C Antibody (Atto 488)

Target: CACNA1C (Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C))

Binding Specificity: AA 848-865, Intracellular

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACNA1C antibody is conjugated to Atto 488

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Characteristics: Anti-CaV1.2 (CACNA1C) Antibody (ABIN7042997, ABIN7043953 and ABIN7043954)) is a highly specific antibody directed against an epitope of rat CaV1.2 channel. The antibody can be used in western blot, immunoprecipitation, immunohistochemistry, immunocytochemistry, and indirect flow cytometry applications. It has been designed to recognize CaV1.2 from mouse, rat, and human samples. \nAnti-CaV1.2 (CACNA1C)-ATTO Fluor-488 Antibody (#ABIN7042998) is directly labeled with an ATTO-488 fluorescent dye. ATTO dyes are characterized by strong absorption (high extinction coefficient), high fluorescence quantum yield, and high photo-stability. The ATTO-488 label is analogous to fluorescein isothiocyanate (FITC) and can be used with filters typically used to detect FITC. Anti-CaV1.2 (CACNA1C)-ATTO Fluor-488 Antibody has been tested in immunohistochemical and immunocytochemical applications and is specially suited to experiments requiring simultaneous labeling of different markers.

Purification: Affinity purified on immobilized antigen.

Immunogen:

Immunogen: Synthetic peptide

Immunogen Sequence: (C)TTKINMDDLQPSENEDKS, corresponding to amino acid residues 848-865 of rat CaV1.2

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: 50 μL double distilled water (DDW).

Concentration: 1 mg/mL

Buffer: Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1 % BSA, 0.05 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: RT,4 °C,-20 °C

Storage Comment:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Target Details for CACNA1C

Target: CACNA1C (Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C))

Alternative Name: CaV1.2 (CACNA1C) (CACNA1C Products)

Synonyms: CACH2 antibody, CACN2 antibody, CACNL1A1 antibody, CCHL1A1 antibody, CaV1.2 antibody, LQT8 antibody, TS antibody, Cav1.2 antibody, Cchl1a1 antibody, MBC antibody, MELC-CC antibody, RATIVS302 antibody, isl antibody, C-LTCC antibody, CHCACHA1C antibody, ICA antibody, cav1.2 antibody, ca(v)1.2 antibody, CAV1.2 antibody, BCR antibody, rbc antibody, calcium voltage-gated channel subunit alpha1 C antibody, calcium channel, voltage-dependent, L type, alpha 1C subunit antibody, voltage-dependent L-type calcium channel subunit alpha-1C antibody, calcium channel, voltage-dependent, L type, alpha 1C subunit S homeolog antibody, Red blood cell count antibody, RNA, 7SL, cytoplasmic 263, pseudogene antibody, CACNA1C antibody, Cacna1c antibody, cacna1c antibody, LOC100442085 antibody, cacna1c.S antibody, RBC antibody, RN7SL263P antibody

Background: Alternative names: Cav1.2, Voltage-dependent L-type Ca2+ channel subunit alpha1C, Cacna1c

Gene ID: 24239

NCBI Accession: NM_000719

UniProt: P22002

Pathways: Hormone Transport, Carbohydrate Homeostasis