Nav1.8 antibody (C-Term, Intracellular) (Atto 594)

Catalog No. ABIN7043654

Product Details anti-Nav1.8 Antibody (Atto 594)

Target: Nav1.8 (SCN10A) (Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A))

Binding Specificity: AA 1943-1956, C-Term, Intracellular

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nav1.8 antibody is conjugated to Atto 594

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Characteristics: Anti-NaV1.8 (SCN10A) Antibody (ABIN7043653, ABIN7045239 and ABIN7045240)) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot, immunoprecipitation, immunocytochemistry, and immunohistochemistry applications. It has been designed to recognize NaV1.8 from rat, human, and mouse samples. \nAnti-NaV1.8 (SCN10A)-ATTO Fluor-594 Antibody (#ABIN7043654) is directly labeled with an ATTO-594 fluorescent dye. ATTO dyes are characterized by strong absorption (high extinction coefficient), high fluorescence quantum yield, and high photo-stability. The ATTO-594 fluorescent label belongs to the class of Rhodamine dyes and can be used with fluorescent equipment typically optimized to detect Texas Red and Alexa-594. Anti-NaV1.8 (SCN10A)-ATTO Fluor-594 Antibody is specially suited to experiments requiring simultaneous labeling of different markers.

Purification: Affinity purified on immobilized antigen.

Immunogen:

Immunogen: Synthetic peptide

Immunogen Sequence: (C)EDEVAAKEGNSPGPQ, corresponding to amino acid residues 1943-1956 of rat NaV1.8

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: 50 μL double distilled water (DDW).

Concentration: 1 mg/mL

Buffer: Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1 % BSA, 0.05 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: RT,4 °C,-20 °C

Storage Comment:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Target Details for Nav1.8

Target: Nav1.8 (SCN10A) (Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A))

Alternative Name: NaV1.8 (SCN10A) (SCN10A Products)

Synonyms: Nav1.8 antibody, PN3 antibody, SNS antibody, hPN3 antibody, Na(V)1.8 antibody, sodium channel, voltage-gated, type X, alpha antibody, sodium voltage-gated channel alpha subunit 10 antibody, Scn10a antibody, SCN10A antibody

Background: Alternative names: NaV1.8 (SCN10A), PN3, SNS, Sodium channel protein type 10 subunit alpha

Gene ID: 29571

NCBI Accession: NM_006514

UniProt: Q63554