Deltex Homolog 1 antibody

Catalog No. ABIN7073794

Product Details anti-Deltex Homolog 1 Antibody

Target: Deltex Homolog 1 (DTX1) (E3 Ubiquitin-protein ligase DTX1 (DTX1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Deltex Homolog 1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse DTX1

Application Details

Application Notes: IHC/IF (H,M,R) 1:600-1:1200/1:200-1:600

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for Deltex Homolog 1

Target: Deltex Homolog 1 (DTX1) (E3 Ubiquitin-protein ligase DTX1 (DTX1))

Alternative Name: DTX1 (DTX1 Products)

Synonyms: hDx-1 antibody, Fxit1 antibody, mKIAA4160 antibody, deltex antibody, dtx antibody, xdtx1 antibody, deltex E3 ubiquitin ligase 1 antibody, deltex homolog 1 (Drosophila) antibody, deltex 1, E3 ubiquitin ligase antibody, deltex 1 L homeolog antibody, deltex 1 S homeolog antibody, DTX1 antibody, dtx1 antibody, Dtx1 antibody, dtx1.L antibody, dtx1.S antibody

Background: The Deltex homolog 1 (E3 ubiquitin-protein ligase DTX1) functions as a ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity). Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it also acts as a negative regulator, depending on the developmental and cell context.

Gene ID: 14357

NCBI Accession: NP_032078

UniProt: Q61010

Pathways: Notch Signaling