FCGBP antibody

Catalog No. ABIN7073926

Product Details anti-FCGBP Antibody

Target: FCGBP (Fc Fragment of IgG Binding Protein (FCGBP))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FCGBP antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Human FCGBP

Application Details

Application Notes: IHC/IF (H,R) 1:500-1:1500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for FCGBP

Target: FCGBP (Fc Fragment of IgG Binding Protein (FCGBP))

Alternative Name: FCGBP (FCGBP Products)

Synonyms: FC(GAMMA)BP antibody, A430096B05Rik antibody, Fc fragment of IgG binding protein antibody, FCGBP antibody, Fcgbp antibody

Background: Fc (Ig constant fragment) receptors ensure protection of the host against foreign antigens, such as microorganisms and pathogens, by removing Ig-coated antigen complexes from circulation. Fc receptors are present on lymphoid and myeloid derivatives, where they mediate endocytosis of Ig-antigen complexes, antibody production in B cells through T cell antigen presentation, cytotoxicity and the release of cytokines and reactive oxygen species. The Fc γ-binding protein (FCGBP) interacts with the Fc portion of IgG and MUC2 to mediate the maintenance of the mucosal structure. FCGBP is a 5,405 amino acid protein that contains twelve TIL (trypsin inhibitory-like) domains and thirteen VWFD domains.

Gene ID: 8857

NCBI Accession: NP_003881

UniProt: Q9Y6R7