IL-17 antibody

Catalog No. ABIN7074342

Product Details anti-IL-17 Antibody

Target: IL-17 (IL17) (Interleukin 17 (IL17))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-17 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse IL-17A

Application Details

Application Notes: IHC/IF (M,R) 1:800-1:1600/1:800-1:1600

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-IL-17 antibody (ABIN7074342)

Sun, Li, Guo, Yin, Huang, Wu, Huang, Feng: "Once-monthly hemin suppresses inflammatory and autoreactive CD4+ T cell responses to robustly ameliorate experimental rheumatoid arthritis." in: iScience, Vol. 24, Issue 10, pp. 103101, (2021) (PubMed).

Shen, Wang, Peng, Liu, Zhang, Zhou, Sun, Wu: "Recombinant Sj16 protein with novel activity alleviates hepatic granulomatous inflammation and fibrosis induced by Schistosoma japonicum associated with M2 macrophages in a mouse model." in: Parasites & vectors, Vol. 12, Issue 1, pp. 457, (2020) (PubMed).

Song, Tan, Wang, Ding, Tang, Xia, Wei, Chen: "Interleukin‑17A facilitates osteoclast differentiation and bone resorption via activation of autophagy in mouse bone marrow macrophages." in: Molecular medicine reports, Vol. 19, Issue 6, pp. 4743-4752, (2019) (PubMed).

Target Details for IL-17

Target: IL-17 (IL17) (Interleukin 17 (IL17))

Alternative Name: IL-17 (IL17 Products)

Synonyms: CTLA8 antibody, IL-17 antibody, IL-17A antibody, IL17 antibody, Ctla-8 antibody, Ctla8 antibody, Il17 antibody, ChIL-17 antibody, IL-17F antibody, IL17A antibody, CTLA-8 antibody, interleukin 17A antibody, IL17A antibody, Il17a antibody

Background: The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).

Gene ID: 16171

NCBI Accession: NP_034682

UniProt: Q62386