Nth Endonuclease III-Like 1 (NTHL1) antibody

Catalog No. ABIN7074866

Product Details

Target: Nth Endonuclease III-Like 1 (NTHL1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse NTH1

Application Details

Application Notes: WB (H) 1:1000-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details

Target: Nth Endonuclease III-Like 1 (NTHL1)

Alternative Name: NTH1 (NTHL1 Products)

Synonyms: psmc3 antibody, psmc3-a antibody, nth-like DNA glycosylase 1 S homeolog antibody, nthl1.S antibody

Background: NTHL1, also named as Endonuclease III-like protein 1 or OCTS3, is a 312 amino acid protein, which belongs to the Nth/MutY family. NTHL1 localizes in the nucleus and is widely expressed with highest levels in heart and lowest levels in lung and liver. NTHL1 Has both an apurinic and/or apyrimidinic endonuclease activity and a DNA N-glycosylase activity and incises damaged DNA at cytosines, thymines and guanines. NTHL1 acts on a damaged strand, 5' from the damaged site and is required for the repair of both oxidative DNA damage and spontaneous mutagenic lesions.

Molecular Weight: 34 kDa

Gene ID: 18207

NCBI Accession: NP_032769

UniProt: O35980