NeuN antibody

Catalog No. ABIN7075479

Product Details anti-NeuN Antibody

Target: NeuN (RBFOX3) (RNA Binding Protein, Fox-1 Homolog 3 (RBFOX3))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NeuN antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse NeuN

Application Details

Application Notes: WB (M,R) 1:1000, IHC/IF (M,R) 1:500-1:1000/1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-NeuN antibody (ABIN7075479)

Yang, Jia, Xiao, Zhao, Lu, Chu, Shao, Pei, Zhang, Chen: "Baicalin Rescues Cognitive Dysfunction, Mitigates Neurodegeneration, and Exerts Anti-Epileptic Effects Through Activating TLR4/MYD88/Caspase-3 Pathway in Rats." in: Drug design, development and therapy, Vol. 15, pp. 3163-3180, (2022) (PubMed).

Jin, Sun, Zhou, Li, Chen, Zhang, Li, Zhang, Yang, Duan: "Pathogenesis Study of Enterovirus 71 Using a Novel Human SCARB2 Knock-In Mouse Model." in: mSphere, Vol. 6, Issue 2, (2021) (PubMed).

Xie, Wang, Pan, Jiang, Feng, Lin: "Apolipoprotein E, low-density lipoprotein receptor, and immune cells control blood-brain barrier penetration by AAV-PHP.eB in mice." in: Theranostics, Vol. 11, Issue 3, pp. 1177-1191, (2021) (PubMed).

Tang, Yan, Wang, Wang, Chen, Xu, Lu, Wang, Liang, Zhang: "Activation of PPAR-β/δ Attenuates Brain Injury by Suppressing Inflammation and Apoptosis in a Collagenase-Induced Intracerebral Hemorrhage Mouse Model." in: Neurochemical research, Vol. 45, Issue 4, pp. 837-850, (2020) (PubMed).

Zhang, Song, Shu, Liang, Shao, Guo, Sun: "Ultrasound improves the outcomes of cardiopulmonary resuscitation in rats by stimulating the cholinergic anti‑inflammatory pathway." in: Molecular medicine reports, Vol. 20, Issue 3, pp. 2675-2684, (2020) (PubMed).

Target Details for NeuN

Target: NeuN (RBFOX3) (RNA Binding Protein, Fox-1 Homolog 3 (RBFOX3))

Alternative Name: NeuN (RBFOX3 Products)

Synonyms: FOX-3 antibody, FOX3 antibody, HRNBP3 antibody, NEUN antibody, Fox-3 antibody, Hrnbp3 antibody, NeuN antibody, Neuna60 antibody, Neun antibody, RGD1560070 antibody, RNA binding fox-1 homolog 3 antibody, RNA binding protein, fox-1 homolog (C. elegans) 3 antibody, RNA binding protein, fox-1 homolog 3 antibody, RBFOX3 antibody, Rbfox3 antibody

Background: NeuN, encoded by FOX3, is a neuron-specific nuclear protein. Anti-NeuN stains exclusively neuronal cells in the central and peripheral nervous systems, especially postmitotic and differentiating neurons, as well as terminally differentiated neurons. Anti-NeuN has been used widely as a reliable tool to detect most postmitotic neuronal cell types. The immunohistochemical staining is primarily localized in the nucleus of the neurons with lighter staining in the cytoplasm.

Molecular Weight: 48 kDa

Gene ID: 52897

NCBI Accession: NP_001020102

UniProt: Q8BIF2