SCN4B antibody

Catalog No. ABIN7075646

Product Details anti-SCN4B Antibody

Target: SCN4B (Sodium Channel, Voltage-Gated, Type IV, beta Subunit (SCN4B))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCN4B antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse SCN4B

Application Details

Application Notes: IHC/IF (M,R) 1:2000-1:4000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for SCN4B

Target: SCN4B (Sodium Channel, Voltage-Gated, Type IV, beta Subunit (SCN4B))

Alternative Name: SCN4B (SCN4B Products)

Synonyms: LQT10 antibody, Navbeta4 antibody, Gm1471 antibody, sb:cb973 antibody, scn4b.2 antibody, si:ch211-139a5.5 antibody, scn4b.1 antibody, scn4b1 antibody, zgc:165389 antibody, sodium voltage-gated channel beta subunit 4 antibody, sodium channel, type IV, beta antibody, sodium channel, voltage-gated, type IV, beta b antibody, sodium channel, voltage-gated, type IV, beta a antibody, SCN4B antibody, Scn4b antibody, scn4bb antibody, scn4ba antibody

Background: The SCN4B protein modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation. Modulates the susceptibility of the sodium channel to inhibition by toxic peptides from spider, scorpion, wasp and sea anemone venom.The protein has been found to be expressed at a high level in dorsal root ganglia, at a lower level in brain, spinal cord, skeletal muscle and heart.

Gene ID: 399548

NCBI Accession: NP_001013408

UniProt: Q7M729