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SOCS7 antibody

SOCS7 Reactivity: Rat IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7075765
  • Target See all SOCS7 Antibodies
    SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))
    Reactivity
    • 41
    • 19
    • 19
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Rat
    Host
    • 40
    • 1
    Rabbit
    Clonality
    • 41
    Polyclonal
    Conjugate
    • 13
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SOCS7 antibody is un-conjugated
    Application
    • 36
    • 23
    • 13
    • 13
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Rat
    Purification
    Affinity purification
    Immunogen
    Recombinant protein corresponding to Mouse SOCS7
    Top Product
    Discover our top product SOCS7 Primary Antibody
  • Application Notes
    IHC/IF (R) 1:650-1:1300/1:400-1:1200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))
    Alternative Name
    SOCS7 (SOCS7 Products)
    Synonyms
    NAP4 antibody, NCKAP4 antibody, SOCS4 antibody, SOCS6 antibody, 2310063P06Rik antibody, C85125 antibody, Nap4 antibody, GB13951 antibody, zgc:175115 antibody, SOCS7 antibody, socs7 antibody, suppressor of cytokine signaling 7 antibody, suppressor of cytokine signaling antibody, SOCS7 antibody, Socs7 antibody, LOC413772 antibody, socs7 antibody
    Background
    SOCS7 regulates signaling cascades probably through protein ubiquitination and/or sequestration. SOCS7 functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. SOCS7 inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA.
    Gene ID
    192157
    NCBI Accession
    NP_619598
    UniProt
    Q8VHQ2
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