TTC7A antibody

Catalog No. ABIN7075875

Product Details anti-TTC7A Antibody

Target: TTC7A (Tetratricopeptide Repeat Domain 7A (TTC7A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTC7A antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse TTC7A

Application Details

Application Notes: WB (H) 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for TTC7A

Target: TTC7A (Tetratricopeptide Repeat Domain 7A (TTC7A))

Alternative Name: TTC7A (TTC7A Products)

Synonyms: 1110035E02Rik antibody, 1700007L07Rik antibody, Ttc7a antibody, fsn antibody, hea antibody, MINAT antibody, TTC7 antibody, Ttc7 antibody, tetratricopeptide repeat domain 7 antibody, tetratricopeptide repeat domain 7A antibody, Ttc7 antibody, TTC7A antibody, Ttc7a antibody

Background: TTC7A (TPR repeat protein 7A) is expressed in enterocytes within the duodenum, ileum, and colon, and has a role in enterocyte survival and function. Mutations in the TTC7A gene can result in a spectrum of intestinal disease, including multiple intestinal atresia (MIA) and very early onset inflammatory bowel diseases (VEOIBD). Functional analysis revealed that TTC7A binds to and facilitates the transport of PI4KIIIa from the trans-Golgi to the plasma membrane, while loss of TTC7A results in dysregulation of PI4KIIIa signaling. This antibody specially recognizes endogenous TTC7A.

Molecular Weight: 100 kDa

Gene ID: 225049

NCBI Accession: NP_082915

UniProt: Q8BGB2

Pathways: Transition Metal Ion Homeostasis