ZC3HC1 antibody

Catalog No. ABIN7076278

Product Details anti-ZC3HC1 Antibody

Target: ZC3HC1 (Zinc Finger, C3HC-Type Containing 1 (ZC3HC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZC3HC1 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse NIPA

Application Details

Application Notes: WB (H) 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for ZC3HC1

Target: ZC3HC1 (Zinc Finger, C3HC-Type Containing 1 (ZC3HC1))

Alternative Name: NIPA (ZC3HC1 Products)

Synonyms: 1110054L24Rik antibody, AU018540 antibody, AU019789 antibody, HSPC216 antibody, Nipa antibody, NIPA antibody, RGD1561099 antibody, zinc finger, C3HC type 1 antibody, zinc finger C3HC-type containing 1 antibody, zinc finger, C3HC-type containing 1 antibody, Zc3hc1 antibody, ZC3HC1 antibody

Background: The regulated oscillation of protein expression is an essential mechanism of cell cycle control. The SCF class of E3 ubiquitin ligases is involved in this process by targeting cell cycle regulatory proteins for degradation by the proteasome, with the F-box subunit of the SCF specifically recruiting a given substrate to the SCF core. NIPA (nuclear interaction partner of ALK) is a human F-box-containing protein that defines an SCF-type E3 ligase (SCFNIPA) controlling mitotic entry. Assembly of this SCF complex is regulated by cell-cycle-dependent phosphorylation of NIPA, which restricts substrate ubiquitination activity to interphase.

Molecular Weight: 55 kDa

Gene ID: 232679

NCBI Accession: NP_001298015

UniProt: Q80YV2