ALDOC antibody

Catalog No. ABIN7111476

This anti-ALDOC antibody is a Mouse Monoclonal antibody detecting ALDOC in WB, IHC, ELISA and IF. Suitable for Human.

Quick Overview for ALDOC antibody (ABIN7111476)

Target: ALDOC (Aldolase C, Fructose-Bisphosphate (ALDOC))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ALDOC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone: 6F3

Product Details anti-ALDOC Antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: aldolase C, fructose-bisphosphate

Isotype: IgG1

Application Details

Application Notes: WB: 1:5000-1:50000, IHC: 1:50-1:500, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for ALDOC

Target: ALDOC (Aldolase C, Fructose-Bisphosphate (ALDOC))

Alternative Name: Aldolase C

Background: Synonyms:ALDOC, Aldolase C, Brain type aldolase, Fructose bisphosphate aldolase C Background:Fructose-bisphosphate aldolase C(ALDOC) reversibly cleaves FBP and F1-P to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate and is strongly expressed in mammalian brain together with ALDOA and is alsopresent in the heart and spleen of some species(PMID:9363598). It is involed in glycolysis as an important enzyme. Phospholipase D2 and inositol 1,4,5-triphosphate interact with ALDOC in signal transduction. Meanwhile, the protein expression of ALDOC has been reported to be regulated in brain tumor, hepatomas, and lung cancer(PMID:21548097).

Molecular Weight: 39 kDa

Gene ID: 230

UniProt: P09972