ASZ1 antibody

Catalog No. ABIN7111610

Product Details anti-ASZ1 Antibody

Target: ASZ1 (Ankyrin Repeat, SAM and Basic Leucine Zipper Domain Containing 1 (ASZ1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASZ1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ankyrin repeat, SAM and basic leucine zipper domain containing 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for ASZ1

Target: ASZ1 (Ankyrin Repeat, SAM and Basic Leucine Zipper Domain Containing 1 (ASZ1))

Alternative Name: ASZ1 (ASZ1 Products)

Synonyms: Gasz antibody, GASZ antibody, gasz antibody, MGC56332 antibody, zgc:56332 antibody, ALP1 antibody, ANKL1 antibody, C7orf7 antibody, CT1.19 antibody, Orf3 antibody, 4933400N19Rik antibody, ORF3 antibody, ankyrin repeat, SAM and basic leucine zipper domain containing 1 antibody, Asz1 antibody, ASZ1 antibody, asz1 antibody

Background: Synonyms:ALP1, ANKL1, Ankyrin like protein 1, ASZ1, C7orf7, GASZ, Orf3 Background:Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation(By similarity).

Molecular Weight: 48-50kd

Gene ID: 136991

UniProt: Q8WWH4