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Claspin antibody
CLSPN
Reactivity: Human
WB, IP, ELISA, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Claspin Antibody
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Target
See all Claspin (CLSPN) Antibodies
Claspin (CLSPN)
Reactivity
All reactivities for Claspin antibodies
Human
Host
All hosts for Claspin antibodies
Rabbit
Clonality
All clonalities for Claspin antibodies
Polyclonal
Conjugate
All conjugates for Claspin antibodies
This Claspin antibody is un-conjugated
Application
All applications for Claspin antibodies
Western Blotting (WB), Immunoprecipitation (IP), ELISA, Immunofluorescence (IF)
Purification
Immunogen affinity purified
Purity
≥95 % as determined by SDS-PAGE
Immunogen
claspin homolog(Xenopus laevis)
Isotype
IgG
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Discover our top product CLSPN Primary Antibody
Alternatives
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Application Details
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Application Notes
WB: 1:200-1:1000, IP: 1:500-1:2000, IF: 1:20-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target Details for Claspin
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Target
Claspin (CLSPN)
Alternative Name
CLSPN (CLSPN Products )
Synonyms
CLSPN antibody, xClaspin antibody, B130025E01 antibody, C85083 antibody, E130314M08Rik antibody, claspin antibody, claspin S homeolog antibody, Clspn antibody, CLSPN antibody, clspn antibody, clspn.S antibody
Background
Synonyms: Background:Required for checkpoint mediated cell cycle arrest in response to inhibition of DNA replication or to DNA damage induced by both ionizing and UV irradiation. Adapter protein which binds to BRCA1 and the checkpoint kinase CHEK1 and facilitates the ATR-dependent phosphorylation of both proteins. Can also bind specifically to branched DNA structures and may associate with S-phase chromatin following formation of the pre-replication complex(pre-RC). This may indicate a role for this protein as a sensor which monitors the integrity of DNA replication forks.
Molecular Weight
240 kDa
Gene ID
63967
UniProt
Q9HAW4
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