IL10RB antibody

Catalog No. ABIN7115413

Product Details anti-IL10RB Antibody

Target: IL10RB (Interleukin 10 Receptor, beta (IL10RB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL10RB antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: interleukin 10 receptor, beta

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for IL10RB

Target: IL10RB (Interleukin 10 Receptor, beta (IL10RB))

Alternative Name: IL10RB (IL10RB Products)

Synonyms: IL10R2 antibody, IL10RB antibody, il10r2 antibody, CDW210B antibody, CRF2-4 antibody, CRFB4 antibody, D21S58 antibody, D21S66 antibody, IL-10R2 antibody, 6620401D04Rik antibody, AI528744 antibody, Crfb4 antibody, D16H21S58 antibody, D21S58h antibody, Il10r2 antibody, RGD1560373 antibody, interleukin 10 receptor subunit beta antibody, interleukin 10 receptor subunit beta S homeolog antibody, interleukin-10 receptor subunit beta antibody, interleukin 10 receptor, beta antibody, IL10RB antibody, il10rb.S antibody, LOC473966 antibody, LOC478404 antibody, il10rb antibody, Il10rb antibody

Background: Synonyms:CRFB4, D21S58, D21S66 Background:Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes(ISG), which contribute to the antiviral state.

Molecular Weight: 42-45 kDa

Gene ID: 3588

UniProt: Q08334