PER2 antibody

Catalog No. ABIN7117321

This Rabbit Polyclonal antibody specifically detects PER2 in WB, ELISA and IP. It exhibits reactivity toward Human and Mouse.

Quick Overview for PER2 antibody (ABIN7117321)

Target: PER2 (Period Circadian Protein 2 (PER2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PER2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-PER2 Antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: period homolog 2

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for PER2

Target: PER2 (Period Circadian Protein 2 (PER2))

Alternative Name: PER2

Background: Synonyms:FASPS, hPER2, KIAA0347, PER2, period homolog 2 Background:PER2, also named as KIAA0347, is a component of the circadian clock mechanism which is essential for generating circadian rhythms. PER2 is a negative element in the circadian transcriptional loop. PER2 influences clock function by interacting with other circadian regulatory proteins and transporting them to the nucleus. It negatively regulates CLOCK|NPAS2-BMAL1|BMAL2-induced transactivation. Defects in PER2 are a cause of familial advanced sleep-phase syndrome (FASPS) which is characterized by very early sleep onset and offset.

Molecular Weight: 136 kDa

Gene ID: 5697

UniProt: O15055