KCNAB2 antibody

Catalog No. ABIN7117722

Product Details anti-KCNAB2 Antibody

Target: KCNAB2 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 2 (KCNAB2))

Reactivity: Rat, Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNAB2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: potassium voltage-gated channel, shaker-related subfamily, beta member 2

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for KCNAB2

Target: KCNAB2 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 2 (KCNAB2))

Alternative Name: KCNAB2 (KCNAB2 Products)

Synonyms: kcnab2 antibody, KCNAB2 antibody, DKFZp459E056 antibody, akr6a5 antibody, kcna2b antibody, kvb-a antibody, kvb2 antibody, kvbeta2 antibody, kvbeta2.1 antibody, kvbeta2.2 antibody, AKR6A5 antibody, HKvbeta2 antibody, HKvbeta2.1 antibody, HKvbeta2.2 antibody, KCNA2B antibody, KV-BETA-2 antibody, Kvbeta2.1 antibody, F5 antibody, I2rf5 antibody, Kcnb3 antibody, kv-beta-2 antibody, potassium channel, voltage gated subfamily A regulatory beta subunit 1 antibody, potassium voltage-gated channel subfamily A regulatory beta subunit 2 antibody, potassium voltage-gated channel, shaker-related subfamily, beta member 2 a antibody, potassium channel, voltage gated subfamily A regulatory beta subunit 2 L homeolog antibody, voltage-gated potassium channel subunit beta-2 antibody, potassium voltage-gated channel, shaker-related subfamily, beta member 2 antibody, kcnab1 antibody, KCNAB2 antibody, kcnab2a antibody, kcnab2.L antibody, LOC397248 antibody, Kcnab2 antibody

Background: Synonyms:KCNA2B, KCNK2 Background:Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits(PubMed:7649300, PubMed:11825900). Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability(By similarity). Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity(By similarity). Promotes potassium channel closure via a mechanism that does not involve physical obstruction of the channel pore(PubMed:7649300, PubMed:11825900). Promotes KCNA4 channel closure(PubMed:7649300, PubMed:11825900). Modulates the functional properties of KCNA5(By similarity). Enhances KCNB2 channel activity(By similarity). Binds NADPH and has NADPH-dependent aldoketoreductase activity(By similarity). Has broad substrate specificity and can catalyze the reduction of methylglyoxal, 9,10-phenanthrenequinone, prostaglandin J2, 4-nitrobenzaldehyde, 4-nitroacetophenone and 4-oxo-trans-2-nonenal(in vitro)(By similarity).

Molecular Weight: 38kd

Gene ID: 8514

UniProt: Q13303