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ProGRP antibody

ProGRP Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7117775
  • Target See all ProGRP Antibodies
    ProGRP (Pro-Gastrin-Releasing Peptide (ProGRP))
    Reactivity
    Human
    Host
    • 1
    Rabbit
    Clonality
    • 1
    Polyclonal
    Conjugate
    • 1
    This ProGRP antibody is un-conjugated
    Application
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    gastrin-releasing peptide
    Isotype
    IgG
    Top Product
    Discover our top product ProGRP Primary Antibody
  • Application Notes
    WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    ProGRP (Pro-Gastrin-Releasing Peptide (ProGRP))
    Alternative Name
    ProGRP (ProGRP Products)
    Synonyms
    BN antibody, GRP-10 antibody, preproGRP antibody, proGRP antibody, gastrin releasing peptide antibody, GRP antibody
    Background
    Synonyms:BN, gastrin releasing peptide, GRP, GRP 10, preproGRP, proGRP Background:Gastrin-releasing peptide, also known as GRP, is normally formed by mucosal cells in the gastric antrum and by the D cells of the pancreatic islets, and its main function is to stimulate secretion of HCl by the gastric mucosa. HCl, in turn, inhibits gastrin formation. Its 148-amino acid preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27-amino acid gastrin-releasing peptide or the 10-amino acid neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation.These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate.
    Molecular Weight
    16kd,32kd
    Gene ID
    2922
    UniProt
    P07492
    Pathways
    Peptide Hormone Metabolism, Hormone Activity
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