TCHP antibody

Catalog No. ABIN7120258

Product Details anti-TCHP Antibody

Target: TCHP (Trichoplein, Keratin Filament Binding (TCHP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCHP antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: trichoplein, keratin filament binding

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for TCHP

Target: TCHP (Trichoplein, Keratin Filament Binding (TCHP))

Alternative Name: TCHP (TCHP Products)

Synonyms: TpMs antibody, A930031F18Rik antibody, AV279199 antibody, RGD1310813 antibody, zgc:136634 antibody, trichoplein keratin filament binding antibody, trichoplein, keratin filament binding antibody, trichoplein, keratin filament binding L homeolog antibody, TCHP antibody, tchp antibody, Tchp antibody, tchp.L antibody

Background: Synonyms: Background:Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells(PubMed:15731013, PubMed:18931701). Is a negative regulator of ciliogenesis(PubMed:25270598).

Molecular Weight: 61 kDa

Gene ID: 84260

UniProt: Q9BT92