USP21 antibody

Catalog No. ABIN7120506

Product Details anti-USP21 Antibody

Target: USP21 (Ubiquitin Specific Peptidase 21 (USP21))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP21 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ubiquitin specific peptidase 21

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for USP21

Target: USP21 (Ubiquitin Specific Peptidase 21 (USP21))

Alternative Name: USP21 (USP21 Products)

Synonyms: USP21 antibody, USP16 antibody, USP23 antibody, ESTM28 antibody, Usp16 antibody, Usp23 antibody, W53272 antibody, ubiquitin specific peptidase 21 antibody, USP21 antibody, Usp21 antibody

Background: Synonyms:Deubiquitinating enzyme 21, Ubiquitin thiolesterase 21, USP16, USP21, USP23 Background:Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di-and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination(By similarity). Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates(PubMed:10799498). Deubiquitinates BAZ2A/TIP5 leading to its stabilization(PubMed:26100909).

Molecular Weight: 63 kDa

Gene ID: 27005

UniProt: Q9UK80