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ZC3HC1 antibody
ZC3HC1
Reactivity: Human, Mouse, Rat
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ZC3HC1 Antibody
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Target
See all ZC3HC1 Antibodies
ZC3HC1
(Zinc Finger, C3HC-Type Containing 1 (ZC3HC1))
Reactivity
All reactivities for ZC3HC1 antibodies
Human, Mouse, Rat
Host
All hosts for ZC3HC1 antibodies
Rabbit
Clonality
All clonalities for ZC3HC1 antibodies
Polyclonal
Conjugate
All conjugates for ZC3HC1 antibodies
This ZC3HC1 antibody is un-conjugated
Application
All applications for ZC3HC1 antibodies
Western Blotting (WB), ELISA
Purification
Immunogen affinity purified
Purity
≥95 % as determined by SDS-PAGE
Immunogen
zinc finger, C3HC-type containing 1
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB: 1:200-1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target Details for ZC3HC1
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Target
ZC3HC1
(Zinc Finger, C3HC-Type Containing 1 (ZC3HC1))
Alternative Name
ZC3HC1 (ZC3HC1 Products )
Synonyms
1110054L24Rik antibody, AU018540 antibody, AU019789 antibody, HSPC216 antibody, Nipa antibody, NIPA antibody, RGD1561099 antibody, zinc finger, C3HC type 1 antibody, zinc finger C3HC-type containing 1 antibody, zinc finger, C3HC-type containing 1 antibody, Zc3hc1 antibody, ZC3HC1 antibody
Background
Synonyms:ZC3HC1, 1110054L24Rik, hNIPA, HSPC216, NIPA Background:Essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1(CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events.
Molecular Weight
55 kDa
Gene ID
51530
UniProt
Q86WB0
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