ZC3H7A antibody

Catalog No. ABIN7126485

Product Details anti-ZC3H7A Antibody

Target: ZC3H7A (Zinc Finger CCCH-Type Containing 7A (ZC3H7A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ZC3H7A antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Coating (Coat), Flow Cytometry (FACS), Immunoprecipitation (IP)

Specificity: The zinc finger CCCH domain-containing protein 7A (ZC3H7A), also known as ZC3H7, HSPC055 or ZC3HDC7, is a 971 amino acid protein that contains a C3H1-type zinc finger domain, three C3H1-type zinc fingers and three TPR repeats. Belonging to the ZC3H12 family, ZC3H7A localizes to the nucleus. Existing as two alternatively spliced isoforms, ZC3H7A is encoded by a gene located on human chromosome 16p13.13. Chromosome 16 makes up nearly 3 % of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of RubinsteinTaybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn s disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human ZC3H7A protein

Isotype: IgG1

Application Details

Application Notes:

Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or HepG2 cells.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for ZC3H7A

Target: ZC3H7A (Zinc Finger CCCH-Type Containing 7A (ZC3H7A))

Alternative Name: ZC3H7A (ZC3H7A Products)

Synonyms: zc3h7 antibody, fa12e01 antibody, fc07f05 antibody, fc38e12 antibody, fc55c11 antibody, zgc:55684 antibody, wu:fa12e01 antibody, wu:fc07f05 antibody, wu:fc38e12 antibody, wu:fc55c11 antibody, zc3hdc7 antibody, MGC81244 antibody, hspc055 antibody, A430104C18Rik antibody, AI447294 antibody, AW556219 antibody, HSPC055 antibody, Zc3h7 antibody, Zc3hdc7 antibody, ZC3H7 antibody, ZC3HDC7 antibody, zinc finger CCCH-type containing 7A antibody, zinc finger CCCH-type containing 7A L homeolog antibody, zinc finger CCCH type containing 7 A antibody, zc3h7a antibody, ZC3H7A antibody, zc3h7a.L antibody, Zc3h7a antibody

Background: Zinc Finger CCCH-Type Containing 7, ZC3HDC7, Zinc Finger CCCH Domain-Containing Protein 7A, HSPC055, FLJ20318, ZC3H7A,ZC3H7A (Transcription Factor)
Cellular localisation: Nucleus

Molecular Weight: 110kDa

Gene ID: 29066, 371856

UniProt: Q8IWR0

Pathways: SARS-CoV-2 Protein Interactome