UROD antibody (AA 121-220) (Cy5)

Catalog No. ABIN709590

Product Details anti-UROD Antibody (Cy5)

Target: UROD (Uroporphyrinogen Decarboxylase (UROD))

Binding Specificity: AA 121-220

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UROD antibody is conjugated to Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human UROD

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for UROD

Target: UROD (Uroporphyrinogen Decarboxylase (UROD))

Alternative Name: UROD (UROD Products)

Synonyms: UROD antibody, pct antibody, wu:fc43e09 antibody, PCT antibody, UPD antibody, AI323803 antibody, Uro-d antibody, porphyrinogen carboxy-lyase antibody, uroporphyrinogen decarboxylase antibody, Uroporphyrinogen decarboxylase UroD antibody, Uroporphyrinogen decarboxylase antibody, UROD antibody, urod antibody, hemE antibody, uroD antibody, Cpin_6502 antibody, Rmar_1187 antibody, LOC5568261 antibody, Mrub_1403 antibody, Arnit_2230 antibody, Ndas_2830 antibody, Mesil_2989 antibody, Trad_0222 antibody, Weevi_0432 antibody, Hipma_1229 antibody, Fluta_0529 antibody, Marky_1143 antibody, Halhy_5610 antibody, Mesop_0899 antibody, Ccan_20670 antibody, Urod antibody

Background:

Synonyms: PCT, UPD, URO D, Uroporphyrinogen decarboxylase, Uroporphyrinogen III decarboxylase.

Background: UROD is the fifth enzyme of the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria. Porphyria cutanea tarda is an autosomal dominant disorder characterized by light-sensitive dermatitis and associated with the excretion of large amounts of uroporphyrin in urine. Hepatoerythropoetic porphyria is a form of porphyria cutanae tarda that may also be a manifestation of benign or malignant hepatic tumors.

Gene ID: 79842