HDAC4/HDAC5/HDAC9 antibody
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- Target See all HDAC4/HDAC5/HDAC9 products
- HDAC4/HDAC5/HDAC9 (HDAC4,HDAC5,HDAC9)
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HDAC4/HDAC5/HDAC9 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
- Cross-Reactivity
- Human, Mouse
- Purification
- Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Immunogen
- Peptide sequence around aa.244~248/257~261/218~222 (T-A-S-E-P) derived from Human HDAC4/HDAC5/HDAC9.
- Isotype
- IgG
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anti-HDAC4,HDAC5,HDAC9 (pSer220), (pSer246), (pSer259) antibody
Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-HDAC4,HDAC5,HDAC9 (Ser220), (Ser246), (Ser259) antibodyReactivity: Human, Mouse WB, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- HDAC4/HDAC5/HDAC9 (HDAC4,HDAC5,HDAC9)
- Alternative Name
- HDAC4/HDAC5/HDAC9 (HDAC4/HDAC5/HDAC9 Products)
- Synonyms
- AHO3 antibody, BDMR antibody, HA6116 antibody, HD4 antibody, HDAC-4 antibody, HDAC-A antibody, HDACA antibody, histone deacetylase 4 antibody, HDAC4 antibody
- Background
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Background:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.
Cress, W.D. and Seto, E. (2000) J Cell Physiol 184, 1-16.
Vigushin, D.M. and Coombes, R.C. (2004) Curr. Cancer Drug Targets 4, 205-218.
Marmorstein, R. (2001) Cell Mol Life Sci 58, 693-703.
Thiagalingam, S. et al. (2003) Ann. N.Y. Acad. Sci. 983, 84-100.Aliases: HD4/HD5/HD9
- UniProt
- P56524, Q9UQL6, Q9UKV0
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