PTPMT1 antibody (AA 101-201) (HRP)

Catalog No. ABIN709730

Product Details anti-PTPMT1 Antibody (HRP)

Target: PTPMT1 (Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1))

Binding Specificity: AA 101-201

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPMT1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PTPMT1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PTPMT1

Target: PTPMT1 (Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1))

Alternative Name: Ptpmt1 (PTPMT1 Products)

Synonyms: im:7137979 antibody, zgc:158719 antibody, DUSP23 antibody, MOSP antibody, PLIP antibody, 1110001D10Rik antibody, 2810004N20Rik antibody, Plip antibody, protein tyrosine phosphatase, mitochondrial 1 antibody, PTPMT1 antibody, ptpmt1 antibody, Ptpmt1 antibody

Background:

Synonyms: DUSP23, FLJ46081, MOSP, NB4 apoptosis/dferentiation related protein, Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1, Phosphoinositide lipid phosphatase, PLIP, PNAS 129, protein tyrosine phosphatase mitochondrial 1, Protein-tyrosine phosphatase mitochondrial 1, pten like phosphatase, PTEN-like phosphatase, PTPM1_HUMAN, Ptpmt1.

Background: This protein phosphatase specifically mediates the dephosphorylation of mitochondrial proteins and consequently plays a central role in ATP production. It probably has a preference for proteins phosphorylated on Ser and/or Thr residues compared to phosphorylation on Tyr residues. It is likely to be involved in the regulation of insulin secretion in pancreatic beta cells.

Gene ID: 399671

Pathways: Inositol Metabolic Process