MAGED1 antibody
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- Target See all MAGED1 Antibodies
- MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MAGED1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Cross-Reactivity
- Mouse, Rat
- Purification
- Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Immunogen
- Peptide with sequence C-EAEARAEARNRMGIGDE derived from Mouse Melanoma-associated antigen D1.
- Isotype
- IgG
- Top Product
- Discover our top product MAGED1 Primary Antibody
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- Application Notes
- WB:1:500-1:1000,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))
- Alternative Name
- Maged1 (MAGED1 Products)
- Synonyms
- MAGED1 antibody, DLXIN-1 antibody, NRAGE antibody, 2810433C11Rik antibody, 5430405L04Rik antibody, DXBwg1492e antibody, Dlixin antibody, Dlxin-1 antibody, Dlxin1 antibody, MAGE-D1 antibody, mFLJ00163 antibody, Nrage antibody, MAGE family member D1 antibody, melanoma antigen family D, 1 antibody, melanoma antigen, family D, 1 antibody, MAGED1 antibody, Maged1 antibody
- Background
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Background: Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds p75NTR and antagonizes its association with TrkA, inhibits cell cycle progression, and facilitates p75NTR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate p53 transcriptional activity and inhibit cell proliferation. Enhances p53 phosphorylation and accumulation.
Zhao Z,et al.(2002) Sci China C Life Sci.45(4):412-20.
Shen WG,et al.(2007) Cell Commun Adhes.14(1):21-31.
Cheresh DA,et al. (1984) J Biol Chem.259(12):7453-9.Aliases: Maged1 antibody, Nrage antibody, Melanoma-associated antigen D1 antibody, Dlxin-1 antibody, MAGE-D1 antigen antibody, Neurotrophin receptor-interacting MAGE homolog antibody
- UniProt
- Q9QYH6
- Pathways
- Neurotrophin Signaling Pathway
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