PSMC2 antibody (AA 101-200) (HRP)

Catalog No. ABIN709985

Product Details anti-PSMC2 Antibody (HRP)

Target: PSMC2 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2))

Binding Specificity: AA 101-200

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMC2 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MSS1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PSMC2

Target: PSMC2 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2))

Alternative Name: MSS1 (PSMC2 Products)

Synonyms: xMSS1 antibody, psmc2 antibody, DDBDRAFT_0168337 antibody, DDBDRAFT_0232966 antibody, DDB_0168337 antibody, DDB_0232966 antibody, MSS1 antibody, Nbla10058 antibody, S7 antibody, NCU02840.1 antibody, zgc:63995 antibody, proteasome 26S subunit, ATPase 2 L homeolog antibody, proteasome (prosome, macropain) 26S subunit, ATPase 2 antibody, 26S protease regulatory subunit 7 antibody, proteasome 26S subunit, ATPase 2 antibody, regulatory particle, ATPase-like-1 antibody, psmc2.L antibody, psmc2 antibody, psmC2 antibody, PSMC2 antibody, rpt-1 antibody, GL50803_21331 antibody, EHI_080890 antibody, UREG_01412 antibody, PITG_10169 antibody, Psmc2 antibody, GL50803_86683 antibody, Tsp_09237 antibody

Background:

Synonyms: 26S protease complex, mammalian suppressor of sgv-1 of yeast, MSS1, Nbla10058, protease 26S subunit 7, proteasome 26S ATPase subunit 2, Proteasome 26S subunit ATPase 2, proteasome 26S subunit ATPase 2, Protein MSS1, PSMC2, putative protein product of Nbla10058, S7 antibody, PRS7_HUMAN.

Background: Proteolytic degradation is critical to the maintenance of appropriate levels of short-lived and regulatory proteins as important and diverse as those involved in cellular metabolism, heat shock and stress response, antigen presentation, modulation of cell surface receptors and ion channels, cell cycle regulation, transcription, and signalling factors. The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus. Others are degraded via the vacuolar pathway which includes endosomes, lysosomes and the endoplasmic reticulum.

Gene ID: 5701

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway