TNFAIP1 antibody (AA 233-316)

Catalog No. ABIN7145827

Product Details anti-TNFAIP1 Antibody

Target: TNFAIP1 (Tumor Necrosis Factor, alpha-Induced Protein 1 (Endothelial) (TNFAIP1))

Binding Specificity: AA 233-316

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFAIP1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 protein (233-316AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TNFAIP1

Target: TNFAIP1 (Tumor Necrosis Factor, alpha-Induced Protein 1 (Endothelial) (TNFAIP1))

Alternative Name: TNFAIP1 (TNFAIP1 Products)

Synonyms: zgc:55302 antibody, wu:fi06b02 antibody, TNFAIP1 antibody, B12 antibody, B61 antibody, BTBD34 antibody, EDP1 antibody, hBACURD2 antibody, Edp-1 antibody, Edp1 antibody, Tnfip1 antibody, tumor necrosis factor, alpha-induced protein 1 (endothelial) antibody, TNF alpha induced protein 1 antibody, TNF alpha induced protein 1 L homeolog antibody, tnfaip1 antibody, TNFAIP1 antibody, Tnfaip1 antibody, tnfaip1.L antibody

Background:

Background: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.

Aliases: TNFAIP1 antibody, BACURD2 antibody, EDP1BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 antibody, hBACURD2 antibody, BTB/POZ domain-containing protein TNFAIP1 antibody, Protein B12 antibody, Tumor necrosis factor antibody, alpha-induced protein 1 antibody, endothelial antibody

UniProt: Q13829