PRKACB antibody (Catalytic Subunit beta) (FITC)

Catalog No. ABIN7146604

Product Details anti-PRKACB Antibody (FITC)

Target: PRKACB (Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB))

Binding Specificity: AA 2-53, Catalytic Subunit beta

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKACB antibody is conjugated to FITC

Application: Please inquire

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human cAMP-dependent protein kinase catalytic subunit beta protein (2-53AA)

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PRKACB

Target: PRKACB (Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB))

Alternative Name: PRKACB (PRKACB Products)

Synonyms: PKACB antibody, XPKAbeta antibody, kin-1 antibody, pkacb antibody, prkacba antibody, PRKACB antibody, prkacb antibody, wu:fz54b03 antibody, zgc:110804 antibody, Pkacb antibody, protein kinase cAMP-activated catalytic subunit beta antibody, protein kinase cAMP-activated catalytic subunit beta S homeolog antibody, protein kinase, cAMP-dependent, catalytic, beta antibody, protein kinase, cAMP-dependent, catalytic, beta b antibody, protein kinase, cAMP dependent, catalytic, beta antibody, PRKACB antibody, prkacb.S antibody, prkacb antibody, Prkacb antibody, prkacbb antibody

Background:

Background: Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis.

Aliases: cAMP-dependent protein kinase catalytic beta subunit isoform 4ab antibody, cAMP-dependent protein kinase catalytic subunit beta antibody, KAPCB_HUMAN antibody, PKA C beta antibody, PKA C-beta antibody, PKACB antibody, Prkacb antibody, protein kinase A catalytic subunit beta antibody, Protein kinase cAMP dependent catalytic beta antibody

UniProt: P22694

Pathways: AMPK Signaling, Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Lipid Metabolism