EIF3I antibody (AA 276-486) (Biotin)

Catalog No. ABIN7147219

Product Details anti-EIF3I Antibody (Biotin)

Target: EIF3I (Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I))

Binding Specificity: AA 276-486

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF3I antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Cdc42-interacting protein 4 protein (276-486AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for EIF3I

Target: EIF3I (Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I))

Alternative Name: TRIP1 (EIF3I Products)

Synonyms: EIF3S2 antibody, PRO2242 antibody, TRIP-1 antibody, TRIP1 antibody, eIF3-beta antibody, eIF3-p36 antibody, 36kDa antibody, D4Ertd632e antibody, Eif3s2 antibody, Trip1 antibody, eIF-3-beta antibody, eIF3 p36 antibody, eif3s2 antibody, hm:zehn0464 antibody, wu:fb62b08 antibody, zgc:56211 antibody, zgc:77823 antibody, CaO19.2967 antibody, eIF-3 39 kDa subunit homolog antibody, eIF3i antibody, eif3-beta antibody, eif3-p36 antibody, eif3i antibody, pro2242 antibody, trip-1 antibody, trip1 antibody, eukaryotic translation initiation factor 3 subunit I antibody, eukaryotic translation initiation factor 3, subunit I antibody, Eukaryotic Initiation Factor antibody, Eukaryotic translation initiation factor 3 subunit I antibody, translation initiation factor eIF3 subunit i antibody, eukaryotic translation initiation factor 3 subunit I L homeolog antibody, EIF3I antibody, Eif3i antibody, eif-3.I antibody, eIF3i antibody, eif3i antibody, TIF34 antibody, eif3i.L antibody

Background:

Background: Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.

Aliases: Cdc42 interacting protein 4 antibody, Cdc42 interaction protein 4 long isoform antibody, Cdc42-interacting protein 4 antibody, CG11341 antibody, CG15015 PA antibody, Cip 4 antibody, CIP4 antibody, CIP4_HUMAN antibody, DCIP4 antibody, hSTP antibody, Protein Felic antibody, Salt tolerant protein antibody, Salt tolerator antibody, STOT antibody, STP antibody, Thyroid hormone receptor interactor 10 antibody, Thyroid receptor interacting protein 10 antibody, Thyroid receptor-interacting protein 10 antibody, TR-interacting protein 10 antibody, TRIP 10 antibody, TRIP-10 antibody, trip10 antibody, Truncated Cdc42 interaction protein 4 antibody

UniProt: Q15642

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Ribonucleoprotein Complex Subunit Organization, Synthesis of DNA