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CDK5RAP2 antibody (Regulatory Subunit)

CDK5RAP2 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7147230
  • Target See all CDK5RAP2 Antibodies
    CDK5RAP2 (CDK5 Regulatory Subunit Associated Protein 2 (CDK5RAP2))
    Binding Specificity
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 996-1111, Regulatory Subunit
    Reactivity
    • 14
    • 1
    • 1
    • 1
    Human
    Host
    • 12
    • 2
    Rabbit
    Clonality
    • 12
    • 2
    Polyclonal
    Conjugate
    • 10
    • 2
    • 1
    • 1
    This CDK5RAP2 antibody is un-conjugated
    Application
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human CDK5 regulatory subunit-associated protein 2 protein (996-1111AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    CDK5RAP2 (CDK5 Regulatory Subunit Associated Protein 2 (CDK5RAP2))
    Alternative Name
    CDK5RAP2 (CDK5RAP2 Products)
    Synonyms
    EGFL5 antibody, C48 antibody, Cep215 antibody, MCPH3 antibody, 2900018K03Rik antibody, an antibody, mKIAA1633 antibody, CDK5 regulatory subunit associated protein 2 antibody, CDK5 regulatory subunit-associated protein 2 antibody, CDK5RAP2 antibody, LOC100156240 antibody, cdk5rap2 antibody, Cdk5rap2 antibody
    Background

    Background: Potential regulator of CDK5 activity via its interaction with CDK5R1. Negative regulator of centriole disengagement (licensing) which maintains centriole engagement and cohesion. Involved in regulation of mitotic spindle orientation (By similarity). Plays a role in the spindle checkpoint activation by acting as a transcriptional regulator of both BUBR1 and MAD2 promoter. Together with MAPRE1, it may promote microtubule polymerization, bundle formation, growth and dynamics at the plus ends. Regulates centrosomal maturation by recruitment of a gamma-tubulin ring complex onto centrosomes (PubMed:26485573).

    Aliases: C48 antibody, CDK5 activator-binding protein C48 antibody, CDK5 regulatory subunit associated protein 2 antibody, CDK5 regulatory subunit-associated protein 2 antibody, CDK5RAP2 antibody, centrosomal protein 215 kDa antibody, Centrosome-associated protein 215 antibody, CEP215 antibody, CK5P2_HUMAN antibody, MCPH3 antibody

    UniProt
    Q96SN8
    Pathways
    M Phase, SARS-CoV-2 Protein Interactome
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