CRHR2 antibody (AA 20-108)

Catalog No. ABIN7148633

Product Details anti-CRHR2 Antibody

Target: CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))

Binding Specificity: AA 20-108

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRHR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse, Rat

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Corticotropin-releasing factor receptor 2 protein (20-108AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CRHR2

Target: CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))

Alternative Name: CRHR2 (CRHR2 Products)

Synonyms: CRF-RB antibody, CRF2 antibody, CRFR2 antibody, HM-CRF antibody, CRF-R2 antibody, CRFR2alpha antibody, CRFR2beta antibody, Crfr2 antibody, Crf2r antibody, CRH-R2 antibody, crhr2-A antibody, corticotropin releasing hormone receptor 2 antibody, corticotropin releasing hormone receptor 2 S homeolog antibody, CRHR2 antibody, Crhr2 antibody, crhr2.S antibody

Background:

Background: G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.

Aliases: Corticotropin releasing hormone receptor 2 antibody, Corticotropin-releasing factor receptor 2 antibody, Corticotropin-releasing hormone receptor 2 antibody, CRF 2 antibody, CRF 2R antibody, CRF R2 antibody, CRF RB antibody, CRF-R-2 antibody, CRF-R2 antibody, CRF2 antibody, CRF2 receptor beta isoform antibody, CRF2R antibody, CRFR 2 antibody, CRFR-2 antibody, CRFR2 antibody, CRFR2_HUMAN antibody, CRH 2R antibody, CRH R2 antibody, CRH-R-2 antibody, CRH-R2 antibody, CRH2R antibody, CRHR 2 antibody, Crhr2 antibody, HM CRF antibody

UniProt: Q13324

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Feeding Behaviour