CYP4V2 antibody (AA 246-525)

Catalog No. ABIN7149277

Product Details anti-CYP4V2 Antibody

Target: CYP4V2 (Cytochrome P450, Family 4, Subfamily V, Polypeptide 2 (CYP4V2))

Binding Specificity: AA 246-525

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP4V2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Cytochrome P450 4V2 protein (246-525AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CYP4V2

Target: CYP4V2 (Cytochrome P450, Family 4, Subfamily V, Polypeptide 2 (CYP4V2))

Alternative Name: CYP4V2 (CYP4V2 Products)

Synonyms: BCD antibody, CYP4AH1 antibody, CYP4V antibody, bcd antibody, cyp4ah1 antibody, MGC147146 antibody, cytochrome P450 family 4 subfamily V member 2 antibody, cytochrome P450 family 4 subfamily V member 2 S homeolog antibody, cytochrome P450, family 4, subfamily V, polypeptide 2 antibody, cytochrome P450, family 4, subfamily v, polypeptide 2 antibody, CYP4V2 antibody, cyp4v2.S antibody, cyp4v2 antibody

Background:

Background: Omega-hydroxylase that oxidizes medium-chain saturated fatty acids and polyunsaturated omega-3 fatty acids, and which plays a role in fatty acid and steroid metabolism in the eye (PubMed:19661213, PubMed:22772592). Catalyzes the omega-hydroxylation of medium-chain saturated fatty acids such as laurate, myristate and palmitate in an NADPH-dependent pathway. The substrate specificity is higher for myristate > laurate > palmitate (C14>C16>C12) (PubMed:19661213). Acts as a polyunsaturated omega-3 fatty acids hydroxylase by mediating oxidation of docosahexaenoate (DHA) to 22-hydroxydocosahexaenoate (PubMed:22772592). Also produces some 21-hydroxydocosahexaenoate. Also converts eicosapentaenoate (EPA) to 20-hydroxyeicosapentaenoate (20-OH-EPA) (PubMed:22772592).

Aliases: BCD antibody, CP4V2_HUMAN antibody, CYP4AH1 antibody, CYP4V 2 antibody, CYP4V2 antibody, Cytochrome P450 4V2 antibody, Cytochrome P450, family 4, subfamily V, polypeptide 2 antibody, Retina CYP4V2 antibody

UniProt: Q6ZWL3