NR5A2 + LRH1 antibody (AA 182-291)

Catalog No. ABIN7161911

This Rabbit Polyclonal antibody specifically detects NR5A2 + LRH1 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for NR5A2 + LRH1 antibody (AA 182-291) (ABIN7161911)

Target: NR5A2 + LRH1 (NR5A2) (Nuclear Receptor Subfamily 5, Group A, Member 2 (NR5A2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NR5A2 + LRH1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-NR5A2 + LRH1 Antibody

Binding Specificity: AA 182-291

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Nuclear receptor subfamily 5 group A member 2 protein (182-291AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NR5A2 + LRH1

Target: NR5A2 + LRH1 (NR5A2) (Nuclear Receptor Subfamily 5, Group A, Member 2 (NR5A2))

Alternative Name: NR5A2

Background:

Background: Binds to the sequence element 5\\\'-AACGACCGACCTTGAG-3\\\' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.

Aliases: Alpha-1-fetoprotein transcription factor antibody, B1-binding factor antibody, B1F antibody, B1F2 antibody, CPF antibody, CYP7A promoter-binding factor antibody, FTF antibody, FTZ F1 antibody, FTZ F1beta antibody, FTZ-F1 antibody, FTZ-F1beta antibody, hB1F 2 antibody, hB1F antibody, hB1F-2 antibody, Hepatocytic transcription factor antibody, Liver receptor homolog 1 antibody, LRH-1 antibody, LRH1 antibody, Nr5a2 antibody, NR5A2_HUMAN antibody, Nuclear receptor subfamily 5 group A member 2 antibody

UniProt: O00482

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway