NR2E3 antibody (AA 112-222) (Biotin)

Catalog No. ABIN7163427

Product Details anti-NR2E3 Antibody (Biotin)

Target: NR2E3 (Nuclear Receptor Subfamily 2, Group E, Member 3 (NR2E3))

Binding Specificity: AA 112-222

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NR2E3 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Photoreceptor-specific nuclear receptor protein (112-222AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NR2E3

Target: NR2E3 (Nuclear Receptor Subfamily 2, Group E, Member 3 (NR2E3))

Alternative Name: NR2E3 (NR2E3 Products)

Synonyms: ESCS antibody, PNR antibody, RNR antibody, RP37 antibody, rd7 antibody, LOC100228348 antibody, A930035N01Rik antibody, wu:fj55b07 antibody, zgc:103631 antibody, nuclear receptor subfamily 2 group E member 3 antibody, nuclear receptor subfamily 2, group E, member 3 antibody, NR2E3 antibody, Nr2e3 antibody, nr2e3 antibody

Background:

Background: Orphan nuclear receptor of retinal photoreceptor cells. Transcriptional factor that is an activator of rod development and repressor of cone development. Binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. Enhances rhodopsin expression. Represses M- and S-cone opsin expression.

Aliases: ESCS antibody, MGC49976 antibody, NR2 E3 antibody, Nr2e3 antibody, NR2E3_HUMAN antibody, Nuclear receptor subfamily 2 group E member 3 antibody, Photoreceptor specific nuclear receptor antibody, Photoreceptor-specific nuclear receptor antibody, PNR antibody, Rd 7 antibody, Rd7 antibody, Retina specific nuclear receptor antibody, Retina-specific nuclear receptor antibody, Retinal degeneration 7 antibody, RNR antibody, RP37 antibody

UniProt: Q9Y5X4

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway