Kcne3 antibody (AA 1-57) (HRP)

Catalog No. ABIN7163986

Product Details anti-Kcne3 Antibody (HRP)

Target: Kcne3 (Potassium Voltage-Gated Channel, Isk-Related Family, Member 3 (Kcne3))

Binding Specificity: AA 1-57

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kcne3 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Potassium voltage-gated channel subfamily E member 3 protein (1-57AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Kcne3

Target: Kcne3 (Potassium Voltage-Gated Channel, Isk-Related Family, Member 3 (Kcne3))

Alternative Name: KCNE3 (Kcne3 Products)

Synonyms: HOKPP antibody, HYPP antibody, MiRP2 antibody, 2210017H05Rik antibody, potassium voltage-gated channel subfamily E regulatory subunit 3 antibody, potassium voltage-gated channel, Isk-related subfamily, gene 3 antibody, KCNE3 antibody, Kcne3 antibody

Background:

Background: Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 (PubMed:12954870). Associated with KCNC4/Kv3.4 is proposed to form the subthreshold voltage-gated potassium channel in skeletal muscle and to establish the resting membrane potential (RMP) in muscle cells. Associated with KCNQ1/KCLQT1 may form the intestinal cAMP-stimulated potassium channel involved in chloride secretion that produces a current with nearly instantaneous activation with a linear current-voltage relationship.

Aliases: KCNE3 antibody, Potassium voltage-gated channel subfamily E member 3 antibody, MinK-related peptide 2 antibody, Minimum potassium ion channel-related peptide 2 antibody, Potassium channel subunit beta MiRP2 antibody

UniProt: Q9Y6H6