CD133 antibody (AA 508-792) (Biotin)

Catalog No. ABIN7364803

Product Details anti-CD133 Antibody (Biotin)

Target: CD133 (PROM1) (Prominin 1 (PROM1))

Binding Specificity: AA 508-792

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD133 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Prominin-1 protein (508-792AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CD133

Target: CD133 (PROM1) (Prominin 1 (PROM1))

Alternative Name: PROM1 (PROM1 Products)

Synonyms: Prom antibody, AC133 antibody, CD133 antibody, Prom-1 antibody, Proml1 antibody, 4932416E19Rik antibody, CORD12 antibody, MCDR2 antibody, PROML1 antibody, RP41 antibody, STGD4 antibody, prominin 1 antibody, Prom1 antibody, PROM1 antibody

Background:

Background: May play a role in cell differentiation, proliferation and apoptosis (PubMed:24556617). Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner (PubMed:20818439).

Aliases: AC133 antibody, Antigen AC133 antibody, CD133 antibody, CORD12 antibody, Hematopoietic stem cell antigen antibody, hProminin antibody, MCDR2 antibody, MSTP061 antibody, OTTHUMP00000217744 antibody, OTTHUMP00000217745 antibody, OTTHUMP00000217746 antibody, PROM1 antibody, PROM1_HUMAN antibody, Prominin I antibody, Prominin like 1 antibody, Prominin like protein 1 precursor antibody, Prominin mouse like 1 antibody, Prominin-1 antibody, Prominin-like protein 1 antibody, Prominin1 antibody, PROML1 antibody, RP41 antibody, STGD4 antibody

UniProt: O43490