SMG7 antibody (AA 694-809) (Biotin)

Catalog No. ABIN7166133

Product Details anti-SMG7 Antibody (Biotin)

Target: SMG7 (Smg-7 Homolog, Nonsense Mediated mRNA Decay Factor (SMG7))

Binding Specificity: AA 694-809

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMG7 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Protein SMG7 protein (694-809AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SMG7

Target: SMG7 (Smg-7 Homolog, Nonsense Mediated mRNA Decay Factor (SMG7))

Alternative Name: SMG7 (SMG7 Products)

Synonyms: 9430023P16Rik antibody, mKIAA0250 antibody, C1orf16 antibody, EST1C antibody, SGA56M antibody, Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) antibody, SMG7, nonsense mediated mRNA decay factor antibody, Smg7 antibody, SMG7 antibody

Background:

Background: Plays a role in nonsense-mediated mRNA decay. Recruits UPF1 to cytoplasmic mRNA decay bodies. Together with SMG5 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation.

Aliases: breast cancer-associated antigen SGA-56M antibody, C1orf16 antibody, EST1 like protein C antibody, EST1 telomerase component homolog C antibody, EST1-like protein C antibody, EST1C antibody, ever shorter telomeres 1C antibody, FLJ23717 antibody, hSMG-7 antibody, nonsense mediated mRNA decay factor (C. elegans) antibody, Protein SMG7 antibody, SGA56M antibody, SMG 7 antibody, SMG-7 homolog antibody, Smg7 antibody, SMG7_HUMAN antibody

UniProt: Q92540