PPP6C antibody (Catalytic Subunit)

Catalog No. ABIN7169292

Product Details anti-PPP6C Antibody

Target: PPP6C (Protein Phosphatase 6, Catalytic Subunit (PPP6C))

Binding Specificity: AA 40-211, Catalytic Subunit

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP6C antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Serine/threonine-protein phosphatase 6 catalytic subunit protein (40-211AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PPP6C

Target: PPP6C (Protein Phosphatase 6, Catalytic Subunit (PPP6C))

Alternative Name: PPP6C (PPP6C Products)

Background:

Background: Catalytic subunit of protein phosphatase 6 (PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. N-terminal domain restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. Downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7.

Aliases: FLJ92648 antibody, MGC12249 antibody, PP 6 antibody, PP6 antibody, PP6C antibody, PPP 6 antibody, PPP 6C antibody, PPP6 antibody, PPP6_HUMAN antibody, Ppp6c antibody, Protein phosphatase 6 catalytic subunit antibody, Serine/threonine protein phosphatase 6 antibody, Serine/threonine protein phosphatase catalytic subunit antibody, Serine/threonine-protein phosphatase 6 catalytic subunit antibody

UniProt: O00743