SLC22A17 antibody (AA 1-99) (Biotin)

Catalog No. ABIN7170141

Product Details anti-SLC22A17 Antibody (Biotin)

Target: SLC22A17 (Solute Carrier Family 22 (Organic Cation Transporter), Member 17 (SLC22A17))

Binding Specificity: AA 1-99

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC22A17 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Solute carrier family 22 member 17 protein (1-99AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SLC22A17

Target: SLC22A17 (Solute Carrier Family 22 (Organic Cation Transporter), Member 17 (SLC22A17))

Alternative Name: SLC22A17 (SLC22A17 Products)

Synonyms: 1700094C23Rik antibody, 24p3R antibody, AU041908 antibody, AW555662 antibody, BOIT antibody, Boct antibody, mBOCT antibody, BOCT antibody, NGALR antibody, NGALR2 antibody, NGALR3 antibody, hBOIT antibody, rBOCT antibody, solute carrier family 22 member 17 antibody, solute carrier family 22 (organic cation transporter), member 17 antibody, solute carrier family 22, member 17 antibody, SLC22A17 antibody, Slc22a17 antibody

Background:

Background: Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis.

Aliases: 24p3 receptor antibody, 24p3R antibody, BOCT antibody, BOIT antibody, Brain type organic cation transporter antibody, Brain-type organic cation transporter antibody, hBOIT antibody, Lipocalin-2 receptor antibody, Neutrophil gelatinase associated lipocalin receptor antibody, Neutrophil gelatinase-associated lipocalin receptor antibody, NGAL receptor antibody, NgalR antibody, NGALR2 antibody, NGALR3 antibody, OTTHUMP00000082690 antibody, OTTHUMP00000082691 antibody, Potent brain type organic ion transporter antibody, S22AH_HUMAN antibody, Slc22a17 antibody, Solute carrier family 22 member 17 antibody, Solute carrier family 22 organic cation transporter member 17 antibody

UniProt: Q8WUG5

Pathways: Transition Metal Ion Homeostasis