SREBF2 antibody (AA 75-164)

Catalog No. ABIN7170782

Product Details anti-SREBF2 Antibody

Target: SREBF2 (Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2))

Binding Specificity: AA 75-164

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SREBF2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Sterol regulatory element-binding protein 2 protein (75-164AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SREBF2

Target: SREBF2 (Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2))

Alternative Name: SREBF2 (SREBF2 Products)

Synonyms: SREBF2 antibody, srebp2 antibody, SREBP2 antibody, zgc:158371 antibody, AI608257 antibody, SREBP-2 antibody, SREBP2gc antibody, bHLHd2 antibody, lop13 antibody, nuc antibody, Srebf2_retired antibody, sterol regulatory element binding transcription factor 2 antibody, sterol regulatory element binding factor 2 antibody, sterol regulatory element binding transcription factor 2 L homeolog antibody, SREBF2 antibody, srebf2 antibody, Srebf2 antibody, srebf2.L antibody

Background:

Background: Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the cholesterol and to a lesser degree the fatty acid synthesis pathway (By similarity). Binds the sterol regulatory element 1 (SRE-1) (5\\\'-ATCACCCCAC-3\\\') found in the flanking region of the LDRL and HMG-CoA synthase genes.

Aliases: AI608257 antibody, bHLHd2 antibody, Class D basic helix-loop-helix protein 2 antibody, OTTHUMP00000028740 antibody, Processed sterol regulatory element-binding protein 2 antibody, SRBP2_HUMAN antibody, SREBF 2 antibody, Srebf2 antibody, SREBF2 protein antibody, SREBP 2 antibody, SREBP-2 antibody, SREBP2 antibody, SREBP2gc antibody, sterol regulatory element binding factor 2 antibody, Sterol regulatory element binding protein 2 antibody, Sterol regulatory element binding transcription factor 2 antibody, Sterol regulatory element-binding transcription factor 2 antibody

UniProt: Q12772

Pathways: Regulation of Lipid Metabolism by PPARalpha