TIGIT antibody (AA 22-141) (Biotin)

Catalog No. ABIN7171346

Product Details anti-TIGIT Antibody (Biotin)

Target: TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))

Binding Specificity: AA 22-141

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIGIT antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human T-cell immunoreceptor with Ig and ITIM domains protein (22-141AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TIGIT

Target: TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))

Alternative Name: TIGIT (TIGIT Products)

Synonyms: VSIG9 antibody, VSTM3 antibody, WUCAM antibody, ENSMUSG00000071552 antibody, Vstm3 antibody, RGD1563191 antibody, T-cell immunoreceptor with Ig and ITIM domains antibody, T cell immunoreceptor with Ig and ITIM domains antibody, TIGIT antibody, Tigit antibody

Background:

Background: Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.

Aliases: DKFZp667A205 antibody, ENSMUSG00000071552 antibody, FLJ39873 antibody, RGD1563191 antibody, T cell immunoreceptor with Ig and ITIM domains antibody, TIGIT antibody, TIGIT_HUMAN antibody, V-set and immunoglobulin domain containing 9 antibody, V-set and immunoglobulin domain-containing protein 9 antibody, V-set and transmembrane domain containing 3 antibody, V-set and transmembrane domain-containing protein 3 antibody, VSIG9 antibody, VSTM3 antibody, Washington University cell adhesion molecule antibody, WUCAM antibody

UniProt: Q495A1

Pathways: Cancer Immune Checkpoints