TRPM2 antibody (AA 60-119) (HRP)

Catalog No. ABIN7172862

Product Details anti-TRPM2 Antibody (HRP)

Target: TRPM2 (Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2))

Binding Specificity: AA 60-119

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRPM2 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Transient receptor potential cation channel subfamily M member 2 protein (60-119AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TRPM2

Target: TRPM2 (Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2))

Alternative Name: TRPM2 (TRPM2 Products)

Synonyms: EREG1 antibody, KNP3 antibody, LTRPC2 antibody, NUDT9H antibody, NUDT9L1 antibody, TRPC7 antibody, Trpm2-predicted antibody, TRPM2 antibody, si:ch73-263b18.1 antibody, 9830168K16Rik antibody, C79133 antibody, Trp7 antibody, Trrp7 antibody, transient receptor potential cation channel subfamily M member 2 antibody, transient receptor potential cation channel, subfamily M, member 2 antibody, transient receptor potential cation channel subfamily C member 7 antibody, TRPM2 antibody, Trpm2 antibody, trpm2 antibody, TRPC7 antibody

Background:

Background: Nonselective, voltage-independent cation channel mediating sodium and calcium ion influx in response to oxidative stress. Extracellular calcium passes through the channel and acts from the intracellular side as a positive regulator in channel activation. Activated by ADP-ribose, nicotinamide adenine dinucleotide (NAD(+)), reactive nitrogen species and arachidonic acid. Inactivated by intracellular ATP. Confers susceptibility to cell death following oxidative stress. Isoform 2 does not seem to be regulated by ADPR. Has ADP-ribose pyrophosphatase activity.

Aliases: EREG 1 antibody, EREG1 antibody, Estrogen responsive element associated gene 1 antibody, Estrogen responsive element associated gene 1 protein antibody, Estrogen-responsive element-associated gene 1 protein antibody, KNP 3 antibody, KNP3 antibody, Long transient receptor potential channel 2 antibody, LTRPC 2 antibody, LTrpC-2 antibody, LTrpC2 antibody, MGC133383 antibody, NUDT9H antibody, NUDT9L1 antibody, putative Ca2+ channel protein antibody, putative Ca2+ channel protein antibody, Transient receptor potential cation channel subfamily M member 2 antibody, Transient receptor potential channel 7 antibody, TRPC 7 antibody, TrpC7 antibody, TRPM 2 antibody, Trpm2 antibody, TRPM2_HUMAN antibody

UniProt: O94759