TNFRSF1B antibody (AA 56-210) (FITC)

Catalog No. ABIN7173831

Product Details anti-TNFRSF1B Antibody

Target: TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))

Binding Specificity: AA 56-210

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFRSF1B antibody is conjugated to FITC

Application: Please inquire

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Tumor necrosis factor receptor superfamily member 10B protein (56-210AA)

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TNFRSF1B

Target: TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))

Alternative Name: TNFRSF1B (TNFRSF1B Products)

Synonyms: CD120b antibody, TBPII antibody, TNF-R-II antibody, TNF-R75 antibody, TNFBR antibody, TNFR1B antibody, TNFR2 antibody, TNFR80 antibody, p75 antibody, p75TNFR antibody, TNF-RII/TNFRSF1B antibody, TNFR-II antibody, TNFRSF1B antibody, TNF-R2 antibody, TNF-alphaR2 antibody, TNFRII antibody, TNFalpha-R2 antibody, Tnfr-1 antibody, Tnfr2 antibody, rank antibody, zgc:163064 antibody, TNF receptor superfamily member 1B antibody, tumor necrosis factor receptor superfamily, member 1b antibody, tumor necrosis factor receptor superfamily, member 1B antibody, TNFRSF1B antibody, Tnfrsf1b antibody, tnfrsf1b antibody

Background:

Background: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.

Aliases: rotein antibody, Apoptosis inducing protein TRICK2A/2B antibody, Apoptosis inducing receptor TRAIL R2 antibody, CD262 antibody, CD262 antigen antibody, Cytotoxic TRAIL receptor 2 antibody, Death domain containing receptor for TRAIL/Apo 2L antibody, Death receptor 5 antibody, DR5 antibody, KILLER antibody, KILLER/DR5 antibody, OTTHUMP00000123492 antibody, OTTHUMP00000123493 antibody, p53 regulated DNA damage inducible cell death receptor(killer) antibody, TNF related apoptosis inducing ligand receptor 2 antibody, TNF-related apoptosis-inducing ligand receptor 2 antibody, TNFRSF10B antibody, TR10B_HUMAN antibody, TRAIL R2 antibody, TRAIL receptor 2 antibody, TRAIL-R2 antibody, TRAILR2 antibody, TRICK2 antibody, TRICK2A antibody, TRICK2B antibody, TRICKB antibody, Tumor necrosis factor receptor like protein ZTNFR9 antibody, Tumor necrosis factor receptor superfamily member 10B antibody, Tumor necrosis factor receptor superfamily, member 10b antibody, ZTNFR9 antibody

UniProt: O14763

Pathways: NF-kappaB Signaling, Apoptosis, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Ubiquitin Proteasome Pathway