PCSK5 antibody (AA 117-452)

Catalog No. ABIN7177762

Product Details anti-PCSK5 Antibody

Target: PCSK5 (Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5))

Binding Specificity: AA 117-452

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCSK5 antibody is un-conjugated

Application: ELISA

Cross-Reactivity: Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Mouse Proprotein convertase subtilisin/kexin type 5 protein (117-452AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PCSK5

Target: PCSK5 (Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5))

Alternative Name: Pcsk5 (PCSK5 Products)

Synonyms: PC5 antibody, PC6 antibody, PC6A antibody, SPC6 antibody, subtilase antibody, PC5/6A antibody, PC5A antibody, b2b1549Clo antibody, b2b585Clo antibody, Pc5 antibody, fur2 antibody, spc6 antibody, spc6A antibody, MGC98915 antibody, PCSK5 antibody, pc6 antibody, spc6a antibody, pcsk5 antibody, zgc:165659 antibody, proprotein convertase subtilisin/kexin type 5 antibody, proprotein convertase subtilisin/kexin type 5 S homeolog antibody, proprotein convertase subtilisin/kexin type 5b antibody, PCSK5 antibody, Pcsk5 antibody, pcsk5.S antibody, LOC528098 antibody, pcsk5 antibody, pcsk5b antibody

Background:

Background: Plays an essential role in pregnancy establishment by proteolytic activation of a number of important factors such as BMP2, CALD1 and alpha-integrins. Likely to represent a widespread endoprotease activity within the constitutive and regulated secretory pathway. Capable of cleavage at the RX(K/R)R consensus motif. May be responsible for the maturation of gastrointestinal peptides. May be involved in the cellular proliferation of adrenal cortex via the activation of growth factors.

Aliases: Pcsk5 antibody, Proprotein convertase subtilisin/kexin type 5 antibody, EC 3.4.21.- antibody, Proprotein convertase 5 antibody, PC5 antibody, Proprotein convertase 6 antibody, PC6 antibody, Subtilisin-like proprotein convertase 6 antibody, SPC6 antibody, Subtilisin/kexin-like protease PC5 antibody

UniProt: Q04592

Pathways: Neurotrophin Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones