FZD6 antibody
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- Target See all FZD6 Antibodies
- FZD6 (Frizzled Family Receptor 6 (FZD6))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FZD6 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human, Mouse
- Purification
- Antigen affinity purification
- Immunogen
- Synthetic peptide of Human FZD6
- Isotype
- IgG
- Top Product
- Discover our top product FZD6 Primary Antibody
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- Application Notes
- ELISA:1:2000-1:10000, IHC:1:100-1:300,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- FZD6 (Frizzled Family Receptor 6 (FZD6))
- Alternative Name
- FZD6 (FZD6 Products)
- Synonyms
- zgc:65879 antibody, zgc:77440 antibody, fz6 antibody, frz6 antibody, Xfrz6 antibody, frizzled6 antibody, frizzled-6 antibody, FZ-6 antibody, FZ6 antibody, HFZ6 antibody, NDNC10 antibody, Frizzled-6 antibody, Fz6 antibody, frizzled class receptor 6 antibody, frizzled class receptor 6 S homeolog antibody, fzd6 antibody, fzd6.S antibody, FZD6 antibody, Fzd6 antibody
- Background
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Background: This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.
Aliases: Frizzled 6 seven transmembrane spanning receptor antibody, Frizzled drosophila homolog of 6 antibody, Frizzled family receptor 6 antibody, Frizzled homolog 6 (Drosophila) antibody, Frizzled homolog 6 antibody, Frizzled-6 antibody, Frizzled6 antibody, Fz 6 antibody, Fz-6 antibody, Fz6 antibody, FZD 6 antibody, Fzd6 antibody, FZD6_HUMAN antibody, Hfz 6 antibody, hFz6 antibody, NDNC10 antibody
- UniProt
- O60353
- Pathways
- WNT Signaling, Tube Formation
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