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FZD6 antibody

FZD6 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7190727
  • Target See all FZD6 Antibodies
    FZD6 (Frizzled Family Receptor 6 (FZD6))
    Reactivity
    • 37
    • 14
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 38
    • 2
    • 2
    • 1
    Rabbit
    Clonality
    • 41
    • 2
    Polyclonal
    Conjugate
    • 30
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FZD6 antibody is un-conjugated
    Application
    • 27
    • 17
    • 7
    • 6
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity
    Human, Mouse
    Purification
    Antigen affinity purification
    Immunogen
    Synthetic peptide of Human FZD6
    Isotype
    IgG
    Top Product
    Discover our top product FZD6 Primary Antibody
  • Application Notes
    ELISA:1:2000-1:10000, IHC:1:100-1:300,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    FZD6 (Frizzled Family Receptor 6 (FZD6))
    Alternative Name
    FZD6 (FZD6 Products)
    Synonyms
    zgc:65879 antibody, zgc:77440 antibody, fz6 antibody, frz6 antibody, Xfrz6 antibody, frizzled6 antibody, frizzled-6 antibody, FZ-6 antibody, FZ6 antibody, HFZ6 antibody, NDNC10 antibody, Frizzled-6 antibody, Fz6 antibody, frizzled class receptor 6 antibody, frizzled class receptor 6 S homeolog antibody, fzd6 antibody, fzd6.S antibody, FZD6 antibody, Fzd6 antibody
    Background

    Background: This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.

    Aliases: Frizzled 6 seven transmembrane spanning receptor antibody, Frizzled drosophila homolog of 6 antibody, Frizzled family receptor 6 antibody, Frizzled homolog 6 (Drosophila) antibody, Frizzled homolog 6 antibody, Frizzled-6 antibody, Frizzled6 antibody, Fz 6 antibody, Fz-6 antibody, Fz6 antibody, FZD 6 antibody, Fzd6 antibody, FZD6_HUMAN antibody, Hfz 6 antibody, hFz6 antibody, NDNC10 antibody

    UniProt
    O60353
    Pathways
    WNT Signaling, Tube Formation
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