TIGIT antibody (AA 22-141)

Catalog No. ABIN7193227

Product Details anti-TIGIT Antibody

Target: TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))

Binding Specificity: AA 22-141

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TIGIT antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)

Purification: purified

Immunogen: Purified recombinant fragment of human TIGIT (AA: extra 22-141) expressed in E. coli.

Clone: 4C5B9

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: N/A

Restrictions: For Research Use only

Handling

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for TIGIT

Target: TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))

Alternative Name: TIGIT (TIGIT Products)

Synonyms: VSIG9 antibody, VSTM3 antibody, WUCAM antibody, ENSMUSG00000071552 antibody, Vstm3 antibody, RGD1563191 antibody, T-cell immunoreceptor with Ig and ITIM domains antibody, T cell immunoreceptor with Ig and ITIM domains antibody, TIGIT antibody, Tigit antibody

Background:

Description: This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity, this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.

Aliases: VSIG9, VSTM3, WUCAM

Molecular Weight: 26.3 kDa

Gene ID: 201633

Pathways: Cancer Immune Checkpoints